Reoviruses are members of the Reoviridae family, whose members possess a nonenveloped icosahedral capsid enclosing a 10-segmented double-stranded RNA genome.

The capacity to modify the reovirus genome facilitates generation of new therapeutic reoviruses. We describe a method for generating replication-competent reoviruses carrying a heterologous transgene.

REOVIRUSES, formerly designated as ECHO virus Type 10,1 have been isolated from cattle,2 chimpanzees,1 monkeys,3 , 4 mice5 and men,1 , 6 7 8 and "antibodies" to one or more types of reovirus have b ...

About 30 percent of Americans are predisposed to celiac disease, but only 1 percent get the disease. A new study finds that a common virus may play a role in determining who gets the disease.

Oncolytic Viral Therapy for Prostate Cancer: Efficacy of Reovirus as a Biological Therapeutic. Cancer Research , 2010; DOI: 10.1158/0008-5472.CAN-09-2408 Cite This Page : ...

Figure 1. The three capsid types formed during AAV production and their therapeutic effect. Capsid titer quantification is commonly performed using optical or antibody-based methods such as ...

EVERETT — Avian reovirus is suspected of killing about 17 crows so far this summer in Snohomish County, according to new data from the state Department of Fish and Wildlife.

Evidence for this theory has been mounting for the past year. On January 10, 2007, Dr. Sheila Fraser of St. James's University Hospital in Leeds, U.K. delivered a paper at the Society of Academic ...

Oncolytics Biotech® Inc. (NASDAQ: ONCY) (TSX: ONC), a leading clinical-stage company specializing in immunotherapy for oncology, today announced new data from the Phase I/II GOBLET clinical trial ...

Novel AAV capsid engineered by Sangamo showed robust penetration of blood-brain barrier (BBB) and widespread transgene expression throughout brain in non-human primates (NHPs) following ...

Agreement grants Lilly rights to employ Sangamo’s novel proprietary capsid, STAC-BBB, for up to five potential disease targets; Sangamo to receive an $18 million upfront license fee and is ...