Six years before the start of the COVID-19 pandemic, an Ebola outbreak in West Africa had people fearing the possibility of a global outbreak. This was the first time many had ever heard of the virus, ...
Electron micrograph of an Ebola virus virion. (CDC/PD) "We're really trying to come up with something that was more practical ...
Measles is caused by a highly contagious virus that’s airborne and spreads easily when an infected person breathes, sneezes or coughs. It is preventable through vaccines, and has been considered ...
Compared with the live-attenuated vaccine, the IRVV shows a good safety profile in vivo, as evidenced by neither virus mutation nor virulence reversion occurring in IRVV-vaccinated animals. A chimeric ...
Caspase cleavage of influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production
This highlights the role of host proteases in regulating IAV exit, relating virion production with host cell state. Influenza A virus Matrix 2 protein (M2) contains a LIR motif which is cleaved by ...
These 19 F-enabled distance NMR experiments are also instrumental for identifying the binding mode and binding site of hexamethylene amiloride in E, paving the way for developing new antiviral drugs ...
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