As previously mentioned, the location at which a DNA strand begins to unwind into two separate single strands is known as the origin of replication. As shown in Figure 1, when the double helix ...
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How Does DNA Unwind? Study Explores Helicase Mechanisms In DNA ReplicationThis study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...
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Mitochondria research reveals mechanism that maintains balance between transcription and replication processesMore information: Shigeru Matsuda et al, TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA, Communications Biology (2025). DOI: 10.1038/s42003 ...
Watson and Crick's discovery of DNA structure in 1953 revealed a possible mechanism for DNA replication. So why didn't Meselson and Stahl finally explain this mechanism until 1958 ...
These findings suggest that TEFM is crucial for the proper regulation of mtDNA replication, particularly at the origin of replication of the heavy strand. In addition, the deletion of TEFM ...
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