We encounter, occasionally, parents who are incapable of making medical decisions on behalf of their incompetent or ...

Nirsevimab, a long-acting monoclonal antibody, was introduced last season (2023–2024) in some countries with the aim of ...

Background Over the last few years, there has been increasing attention to the involvement of the central nervous system in Duchenne muscular dystrophy (DMD). The aim of this study was to assess the ...

The relief of pain and anxiety associated with painful or invasive procedures is a top priority in paediatrics. A ‘Sounding Board’ in the New England Journal of Medicine 30 years ago stated that ‘The ...

Objective To evaluate the efficacy differentials among corticosteroid regimens by type, dosage and duration, we conducted a systematic review and network meta-analysis of randomised controlled trials ...

The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled ...

Many additives, some of which have no nutritional value, can be legally used in processed foods. They intensify colour, thicken, increase shelf life and enhance flavour. Regulatory authorities issue ...

Aim DRC software aims to reduce dosing errors, 1 however, it has been linked to ‘alert fatigue’, a phenomenon which causes prescribers to potentially override alerts despite being clinically relevant.

Objectives Develop a score summarising how successfully a child with any surgical condition has been treated, and test the clinical validity of the score. Design Discrete choice experiment (DCE), and ...

Objectives Historically diagnoses of Trisomy 13 (T13) and Trisomy 18 (T18) have been associated with a very poor prognosis. Median survival of full T18 is 14days, T13 is 10days and 3-month survival is ...

Why did you do this work?NICE, BTS and SIGN asthma guidelines emphasise the importance of education in supporting patients’ self-management to improve clinical outcomes. 1 2 We saw potential to ...

Background Children with autism spectrum disorder (ASD) face unique challenges in acute emergency presentations, resulting in longer wait times, heightened distress, and communication barriers.